Fibrosis is a wound-healing response to chronic liver injury and can result in cirrhosis if left untreated. There is considerable size variation between individuals, with the standard reference range for men being 970–1,860 g (2.14–4.10 lb) and for women 600–1,770 g (1.32–3.90 lb). JAAD Case Reports is an open access journal dedicated to publishing case reports related to diseases of the skin, hair, and nails. 58 The various patterns of liver involvement in … ... the overall features are consistent with metabolic associated fatty liver disease with cirrhosis. All submissions are peer reviewed. Microscopic (histologic) description. Structure. 57 Chronic intrahepatic venous stasis can also predispose to intrahepatic thrombi, which can accelerate fibrosis and eventually lead to cirrhosis. A human liver normally weighs approximately 1.5 kg (3.3 lb) and has a width of about 15 cm (6 in). If accepted for publication, authors are requested to pay an article processing fee per article. The liver is a reddish-brown, wedge-shaped organ with two lobes of unequal size and shape. Autoimmune hepatitis, formerly called lupoid hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells, causing the liver to be inflamed.Common initial symptoms include fatigue or muscle aches or signs of acute liver inflammation including fever, jaundice, and right upper quadrant abdominal pain. Likelihood of liver cirrhosis in patients with cHCC-CC has been reported to be intermediate between the high proportion seen in patients with hepatocellular carcinoma and the lower prevalence in patients with intrahepatic cholangiocarcinoma
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